PolySialic Acid Nanoparticles Actuate Complement-Factor-H-Mediated Inhibition of the Alternative Complement Pathway: A Safer Potential Therapy for Age-Related Macular Degeneration

The alternative pathway of the complement system is implicated in the etiology of age-related macular degeneration (AMD).Complement depletion with pegcetacoplan and avacincaptad pegol are FDA-approved treatments for geographic atrophy in AMD that, while effective, have Wireless Chargers clinically observed risks of choroidal neovascular (CNV) conve

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Factors associated with COVID-19 vaccine acceptance and hesitancy among residents of Northern California jails

Carceral facilities are high-risk settings for COVID-19 transmission.Factors associated with COVID-19 vaccine acceptance and hesitancy among incarcerated individuals are poorly understood, especially among jail residents.Here, we conducted a retrospective review of electronic health record (EHR) data on COVID-19 vaccine uptake in custody and additi

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